2006CB504803), the Twelve Five-year Strategy of China (nos. 47.9%), deficiency (412 instances, 18.6%), stagnation (148 instances, 6.7%), deficiency (65 instances, 2.9%), warmth (60 instances, 2.7%), and blood deficiency (23 instances, 1.0%). 3.3. Core Medicine of Chinese Natural Prescription (Numbers ?(Numbers1,1, ?,2,2, ?,3,3, and Table 2) Open in a separate window Number 1 Overall scenario of Chinese herbal prescription medicine for TCM syndrome element Deficiency. Open in a separate window Number 2 Overall scenario of Chinese natural prescription medicine for TCM syndrome element blood stasis. Open in a separate window Number 3 Overall scenario of Chinese natural prescription medicine for TCM syndrome element turbid phlegm. Table 2 Core medicine of Chinese natural prescription. deficiencyTangshen, Heterophylly Falsestarwort Root, Largehead Atractylodes Rhizome, Milkvetch Root, Radix Glycyrrhizae, Indian Breads, and Chinese Day deficiency, blood stasis, and turbid phlegm. Use complex network clustering method to display the core Chinese herbal medicine of three TCM syndrome elements. With all the Chinese herbal medicine used in the treatment options of a syndrome element as the nodes, the medicine in compatibility offers interconnected feature, and the number of interconnected is the medicine related rate of recurrence. The most frequently related nodes with additional medicine have the most critical role in all the medication of this syndrome element. Therefore, the densest nodes are the core prescription medicine. 3.4. Optimization and Effectiveness Evaluation of Prescriptions for Different TCM Syndrome Elements in Individuals with UA (Table 3) Table 3 Optimizing prescription of different TCM syndrome elements for UA individuals. deficiencyMilkvetch Root + Tangshen + Indian Breads + Largehead Atractylodes Rhizome0.96630 deficiency for individuals with UA, the combination of Danshen Root + Chinese Angelica + Safflower + Red Peony Root + Szechwan Azelastine HCl (Allergodil) Lovage Rhizome, Orange Fruit is the optimizing prescription of TCM syndrome element blood stasis for individuals with UA, and the combination of Rabbit Polyclonal to Mucin-14 Snakegourd Fruit + Longstamen Onion Bulb + Pinellia Tuber + Dried Tangerine peel + Largehead Atractylodes Rhizome + Platycodon Root is the optimizing prescription of TCM syndrome element turbid phlegm for individuals with UA. For popular titles of Chinese natural medicine, see Table 4. Table 4 Popular names of Chinese herbal medicine. deficiency individuals is Milkvetch Root + Si junzi decoction without Radix Glycyrrhizae, prescription of blood stasis recommended Danshen Root + Tao Hong Siwu decoction plus Orange Fruit without rehmanniae radix, prescription of turbid phlegm recommended Gualou xiebai banxia decoction plus Dried Tangerine peel, Largehead Atractylodes Rhizome, Platycodon Root. Those are recommendations from strict mathematical model stimulating dynamic TCM prescription process, which are in line with standard medical thinking and put forward proposals worthy of strict medical study. Besides that, the prescriptions derived from actual medical data are experiences and summaries of medical practice with substantial medical significance. The Azelastine HCl (Allergodil) proposals are in conformity with the medical normal conditions and demonstrate the reliability and operability of optimizing prescription method in effectiveness evaluation on the other hand. It should be noted the rigorous mathematical assessment method using with this study to Azelastine HCl (Allergodil) Azelastine HCl (Allergodil) observe short-term and long-term effectiveness of prescriptions in order to discover initial optimizing recommendations is limited to the number of individuals, indicators, follow-up time, and so on the extension value should apply modern medical research methods such as case-control trail to do retrospectively summarized assessment or large-scale, multicenter, and large sample RCT for further verification to increase the level of evidence-based medicine. However, in complex data of medical practice, the effectiveness of the individuals is affected by many complicated factors; this formulation optimization idea still offers great significance in effectiveness assessment and screening treatment plan, and it also provides us an.