The prevalence of HBsAg, anti-HBc and anti-HBs among pregnant women older than 20 years of age was 4.54, 5.69 and 0.61 times that among pregnant women younger than 20 years, respectively. women who were HBVDNA positive. Results The prevalence of HBsAg, anti-HBc and anti-HBs among 4,536 pregnant women was 5.49%, 29.65% and 58.55%, respectively. The prevalence of HBsAg, anti-HBc Rabbit Polyclonal to PLCB3 and anti-HBs among pregnant women older than 20 years of age was significantly different compared to pregnant women more youthful than 20 years of age (4.54, 5.69 and 0.61 times, prevalence older vs. more youthful, respectively. = 4.54, 95% CI: 1.12~18.43). This higher prevalence of HBsAg among pregnant women older than 20 years was significant higher compared to pregnant women more youthful than 20 years (P 0.05) (Table ?(Table11). Table 1 The prevalence of HBsAg, anti-HBc and anti-HBs among pregnant women in the different age groups = 5.69, 95%CI: 3.07~10.54). This higher prevalence of DBPR112 anti-HBc among pregnant women older than 20 years was significant higher compared to pregnant women more youthful than 20 years (P 0.01) (Table ?(Table11). The prevalence of anti-HBs among pregnant women was 58.55% (2656/4536). The prevalence of anti-HBs among pregnant women older than 20 years (58.17%) was 0.61 times that among pregnant women younger than 20 years (69.48%) (= 0.61, 95%CI: 0.43~0.87). This lesser prevalence of anti-HBs among pregnant women older than 20 years was significant lesser compared to pregnant women younger than 20 years (P 0.05) (Table ?(Table11). HBeAg status and HBVDNA weight among HBsAg positive pregnant women HBeAg and HBVDNA were analyzed among the 249 HBsAg positive pregnant women. Of the 249 women, 167 (67.07%) were HBeAg positive and 204 (81.93%) were HBVDNA positive. Of the 204 HBVDNA positive women, only 37 (14.86%) had HBVDNA 107 IU/ml. All pregnant women with HBVDNA 107 IU/ml were HBeAg positive and all those who were HBVDNA negative were HBeAg unfavorable (Table ?(Table22). Table 2 HBeAg status and HBVDNA weight among HBsAg positive pregnant women thead valign=”top” th align=”center” valign=”bottom” rowspan=”1″ colspan=”1″ HBVDNA hr / /th th align=”center” valign=”bottom” rowspan=”1″ colspan=”1″ HBeAg positive hr / /th th align=”center” valign=”bottom” rowspan=”1″ colspan=”1″ HBeAg unfavorable hr / /th th align=”center” valign=”bottom” rowspan=”1″ colspan=”1″ Total hr / /th th align=”center” rowspan=”1″ colspan=”1″ IU/ml /th th align=”center” rowspan=”1″ colspan=”1″ n=167 /th th align=”center” rowspan=”1″ colspan=”1″ n=82 /th th align=”center” rowspan=”1″ DBPR112 colspan=”1″ n=249 /th /thead 12 hr / 0(0%) hr / 45(54.88%) hr / 45(18.07%) hr / (12C50) hr / 2(1.20%) hr / 9(39.02%) hr / 11(4.42%) hr / (50- 107) hr / 128(76.64%) hr / 28(6.10%) hr / 156(62.65%) hr / ( 107)37(22.16%)0(0%)37(14.86%) Open in a separate window HBV contamination of infants There were 249 infants whose mothers were HBsAg positive and were vaccinated with standard immunoprophylaxis and followed up at 7 months of age. There were 214 (85.94%) infants who tested anti-HBs positive only. There were 12 (4.82%) infants who were HBsAg and HBVDNA positive, and their mothers were HBeAg positive and HBVDNA 107 IU/ml (Table ?(Table3).3). There were 2 (16.67%) DBPR112 infants who were anti-HBs positive among the 12 HBsAg positive infants.The anti-HBs titers were 547.25 mIU/ml and 1224.58 mIU/ml, respectively. Table 3 Serological and virological profile for the 12 infected mother-infant pairs thead valign=”top” th align=”center” valign=”bottom” rowspan=”1″ colspan=”1″ No. hr / /th th colspan=”5″ align=”center” valign=”bottom” rowspan=”1″ Mothers hr / /th th colspan=”5″ align=”center” valign=”bottom” rowspan=”1″ Infants hr / /th th align=”center” rowspan=”1″ colspan=”1″ ? /th th align=”center” rowspan=”1″ colspan=”1″ HBsAg /th th align=”center” rowspan=”1″ colspan=”1″ HBeAg /th th align=”center” rowspan=”1″ colspan=”1″ anti-HBc /th th align=”center” rowspan=”1″ colspan=”1″ anti-HBs /th th align=”center” rowspan=”1″ colspan=”1″ HBVDNA (IU/ml) /th th align=”center” rowspan=”1″ colspan=”1″ HBsAg /th th align=”center” rowspan=”1″ colspan=”1″ HBeAg /th th align=”center” rowspan=”1″ colspan=”1″ anti-HBc /th th align=”center” rowspan=”1″ colspan=”1″ anti-HBs /th th align=”center” rowspan=”1″ colspan=”1″ HBVDNA (IU/ml) /th /thead 1 hr / + hr / + hr / + hr / – hr / 5.56107 hr / + hr / + hr / + hr / – hr / 1.14107 hr / 2 hr / + hr / + hr / + hr / – hr / 5.49108 hr / + hr / + hr / + hr / + hr / 1.73107 hr / 3 hr / + hr / + hr / + hr / – hr / 2.37108 hr / + hr / + hr / + hr / – hr / 2.80108 hr / 4 hr / + hr / + hr / + hr / – hr / 4.12108 hr / + hr / + hr / + hr / + hr / 2.21107 hr / 5 hr / + hr / + hr / + hr / – hr / 2.89109 hr / + hr / + hr / + hr / – hr / 9.63108 hr / 6 hr / + hr / + hr / + hr / – hr / 2.16107 hr / + hr / + hr / + hr / – hr / 6.98107 hr / 7 hr / + hr / + hr / + hr.